Hormone Therapy for Breast Cancer

Hormone replacement therapy and breast cancer

The concern that postmenopausal hormone replacement therapy (HRT) may cause cancer of the breast has lead to an enormous volume of research in epidemiology, endocrinology and tumour cell biology. The epidemiology has become extremely sophisticated because the anticipated effect is small and there are several confounding factors. The consensus today is that long-term HRT (>10 years) is associate...

Hormone replacement therapy and breast cancer.

Hormone-replacement therapy (HRT) has been available for many years, but the important question of its place in development and progression of breast cancer remains controversial; provision of reliable risk estimates has been hampered by a lack of controlled data. Observational evidence suggests that the risk of breast cancer may be increased only if HRT is used long term (ie, for longer than 1...

Breast cancer and hormone replacement therapy.

Understanding the association between hormone replacement therapy (HRT), the diagnosis of breast cancer, and the clinical outcome of women who develop breast cancer in the setting of HRT continue to present important challenges for health professionals and the public. The general impression in the medical community is that breast cancer is diagnosed more frequently after prolonged HRT; however,...

Skin Reaction in Radiation Therapy for Breast Cancer

Introduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the present study, the severity of acute skin changes and the underlying causes were investigated in pati...

Hormone replacement therapy for breast cancer survivors: an answered question?